Liquet Medical – Versus: The First Real-Time Hemodynamics-Led Thrombolytics Catheter
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In this episode we go deep on the Versus™ Catheter from Liquet Medical – the first 510(k)-cleared catheter that combines controlled infusion of physician-specified fluids (including thrombolytics) into the pulmonary arteries with simultaneous, continuous pulmonary artery and intracardiac pressure monitoring.
John Schindler (CEO & Founder) shares:
- How losing his mother to a massive PE at age 3 drove a 30-year vascular medtech journey that ended with Versus
The three breakthrough features:
- Dual-tip design with independent infusion channels – treat both lungs from one venous access
- Integrated pressure sensors on each tip – live PA pressure waveforms while infusing
- Real-time hemodynamic feedback – titrate dose, rate, and location based on live RV and PA pressure response
Why only ~14–30 % of intermediate-risk PE patients who could benefit from advanced therapy actually receive it today
The massive RCTs coming 2026–2027 (HI-PEITHO, PEERLESS-2, PE-TRACT, etc.) that could dramatically expand catheter-based treatment
FDA 510(k)-cleared indications:
- Controlled and selective infusion of physician-specified fluids, including thrombolytics, into the pulmonary artery vasculature in adult patients
- Assessment of a patient’s hemodynamic condition through direct intracardiac and pulmonary artery pressure monitoring